PUBLICATIONS
2023
Sego TJ, Comlekoglu T, Peirce SM, DeSimone DW, Glazier JA. (2023) General, open-source vertex modeling in biological applications using Tissue Forge. Scientific Reports. 13, 17886. https://doi.org/10.1038/s41598-023-45127-x
Leonard-Duke J, Bruce AC, Peirce SM, Taite LJ. (2023) Variations in mechanical stiffness alter microvascular sprouting and stability in a PEG hydrogel model of idiopathic pulmonary fibrosis. Microcirculation. Aug;30(5-6):e12817. PMID: 37248193.
Ruddiman CA, Peckham R, Luse MA, Chen YL, Kuppusamy M, Corliss BA, Hall PJ, Lin CJ, Peirce SM, Sonkusare SK, Mecham RP, Wagenseil JE, Isakson BE. (2023) Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1. JCI Insight. May 8;8(9):e165715. PMID: 37014698.
Skalnik CJ, Cheah SY, Yang MY, Wolff MB, Spangler RK, Talman L, Morrison JH, Peirce SM, Agmon E, Covert MW. (2023) Whole-cell modeling of E. coli colonies enables quantification of single-cell heterogeneity in antibiotic responses. PLoS Comput Biol. Jun 16;19(6):e1011232. PMID: 37327241.
![Julie and Lakeshia Microcirculation - 2023 - Leonard‐Duke[27].jpg](https://static.wixstatic.com/media/398e3e_ccfcabf929664108b8f55b2f91edc8e5~mv2.jpg/v1/fill/w_145,h_193,al_c,q_80,usm_2.00_1.00_0.00,enc_auto/Julie%20and%20Lakeshia%20Microcirculation%20-%202023%20-%20Leonard%E2%80%90Duke%5B27%5D.jpg)
2022
Sivakumar N, Mura C, Peirce SM. (2022) Innovations in integrating machine learning and agent-based modeling of biomedical systems. Front. Syst. Biol., 10 November 2022 Sec. Multiscale Mechanistic Modeling Volume 2. https://doi.org/10.3389/fsysb.2022.959665,
Rikard MS, Kim B, Michel J, Peirce SM, Barnes LE, Williams MD. (2022) Identifying Individual Social Risk Factors Using Unstructured Data in Electronic Health Records which are Associated with Adverse Clinical Outcomes. Social Science & Medicine - Population Health. 19:101210. PMID: 36111269.
Pruett L, Taing AL, Singh NS, Peirce SM, Griffin DR. (2022) In silico optimization of heparin microislands in microporous annealed particle (MAP) hydrogel for endothelial cell migration. Acta Biomaterialia. 148:171-180. PMID: 35660016.
Sivakumar N, Warner HV, Peirce SM, Lazzara MJ. (2022) A computational modeling approach for predicting multicell spheroid patterns based on signaling-induced differential adhesion. PLOS Computational Biology. 18(11):e1010701. PMID: 36441822.
Bour R, Garner G, Peirce SM, Christ G. (2022) Development and evaluation of a fully enclosed bioreactor environment (FEBE) for automated biofabrication of implantable tissue engineered muscle repair constructs. Tissue Engineering – Part A. 28:179-180.
Sun N, Bruce AC , Ning B, Cao R, Wang Y, Zhong F, Peirce SM , and Song Hu. (2022) Photoacoustic Microscopy of Vascular Adaptation and Tissue Oxygen Metabolism during Cutaneous Wound Healing. Biomedical Optics. 13 (5), 2695-2706. Editor’s Pick.
Varhue WB, Raneb A, Castellanos-Sanchez R, Peirce SM, Christ G, Swami NS. (2022) Perfusable cell-laden micropatterned hydrogels for delivery of spatiotemporal vascular-like cues to tissues. Organs on a Chip. Available online 15 January 2022, 100017.
Agmon A, Spangler AK, Skalnik CJ, Poole W, Peirce SM, Morrison JH, Covert MW. (2022) Vivarium: an interface and engine for integrative multiscale modeling in computational biology. Bioinformatics.
38(7):1972-1979. PMID: 35134830.
Harris AR, Esparza S, Azimi MS, Azar FN, Cornelison RC, Llaneza DC, Belanger M, Mathew A, Tkachenko S, Perez MJ, Rosean CB, Bostic RR, Tate KM, Peirce-Cottler S, Paquette C, Mills A, Landen C, Saucerman JJ, Dillon P, Pompano RR, Rutkowski MA, Munson JM. (2022) Platinum chemotherapy induces lymphangiogenesis in cancerous and healthy tissues that can be prevented with adjuvant anti-VEGFR3 therapy. Frontiers in Oncology. DOI=10.3389/fonc.2022.801764.
Torres-Castro K, Azimi MS, Varhue WB, Honrado C, Peirce SM, Swami NS. (2022) Biophysical quantification of reorganization dynamics of human pancreatic islets during co-culture with adipose-derived stem cells. Analyst.
2021
Rikard M, Myers PJ, Almquist J, Gennemark P, Bruce AC, Waberg M, Fritsche-Danielson R, Hansson KM, Lazzara MJ, Peirce SM. (2021) Mathematical Model Predicts that Acceleration of Diabetic Wound Healing is Dependent on Spatial Distribution of VEGF-A mRNA (AZD8601). Cellular and Molecular Bioengineering. 4(4):321-338. PMID: 34290839.
Virgilio K, Jones B, Miller E, Ghajar-Rahimi E, Martin K, Peirce SM, Blemker SS. (2021) Computational models provide insight into in vivo studies and reveal the complex role of fibrosis in mdx muscle regeneration. Annals of Biomedical Engineering. 49(2):536-547. PMID: 32748106.
Westman AM, Peirce SM, Christ GJ, Blemker SS. (2021) Agent-based model provides insight into the mechanisms behind failed regeneration following volumetric muscle loss injury. PLoS Comput Biol. 17(5):e1008937. PMID: 33970905.
Mendelson AA, Lam F, Peirce SM, Murfee WL. (2021) Clinical perspectives on the microcirculation. Microcirculation. 28(3):e12688. PMID: 33629399.
Dolan RM, Motherwell J, Hodges N, Suarez-Martinez AD, McFetridge P, Gomillion C, Sarntinoranont M, Peirce SM, Anderson C, Murfee WL. (2021) Biomimetic Models of the Microcirculation for Scientific Discovery and Therapeutic Testing. Vascularization for Tissue Engineering and Regenerative Medicine. 321.342. Springer Publishing.
2020
Hannan RT, Miller AE, Hung R-C, Sano C, Peirce SM, Barker TH. (2020) Extracellular matrix remodeling associated with bleomycin-Induced lung injury supports pericyte-to-myofibroblast transition. Matrix Biology Plus. 10:100056. PMID: 34195593.
Ray CH, Corliss BA, Bruce AC, Kesting S, Dey P, Mansour J, Seaman SA, Smolko CM, Mathews C, Dey B, Owens GK, Peirce SM, Yates PA. (2020) Myh11+ microvascular mural cells and derived mesenchymal stem cells promote retinal fibrosis. Scientific Reports. 25;10(1):15808. PMID: 32978500.
Leonard-Duke J, Evans S, Hannan RT, Barker TH, Bates JHT, Bonham CA, Moore BB, Kirschner DE, Peirce SM. (2020) Multi-scale Models of Lung Fibrosis. Matrix Biology. 91-92:35-50. PMID: 32438056.
Corliss BA, Ray HC, Doty RW, Mathews C, Sheybani N, Fitzgerald K, Prince R, Kelly-Goss M, Murfee WL, Chappell J, Owens G, Yates PA, Peirce SM. (2020) Pericyte Bridges in Homeostasis and Hyperglycemia. Diabetes. 69(7):1503-1517. PMID: 32321760.
Almquist J, Rikard M, Wågberg M, Bruce AC, Gennemark P, Fritsche-Danielson R, Chien KR, Peirce SM, Hansson K Lundahl A. (2020) Model-based analysis reveals a sustained and dose-dependent acceleration of wound healing by VEGF-A mRNA (AZD8601). CPT: Pharmacometrics & Systems Pharmacology. 9(7):384-394. PMID: 32438492.
Tavakol DN, Schwager SC, Jeffries LA, Bruce A, Corliss BA, DeRosa CA, Fraser CL, Peirce SM, Cottler PS. (2020) Oxygen-Sensing Biomaterial Construct for Clinical Monitoring of Wound Healing. Advances in Skin & Wound Care. 33(8):428-436. PMID: 32701253.
Corliss BA, Doty RW, Mathews C, Yates PA, Zhang T, Peirce SM. (2020) REAVER: A Program for Improved Analysis of High-resolution Vascular Network Images.Microcirculation. 27(5):e12618. PMID: 32173962.
Sun N, Ning B, Bruce AC, Cao R, Seaman SA, Wang T, Fritsche-Danielson R, Carlsson LG, Peirce SM, Hu S. (2020) In vivo imaging of hemodynamic redistribution and arteriogenesis across microvascular network. Microcirculation. 27(3):e12598. PMID: 31660674.
Bour RK, Sharma PR, Turner JS, Hess WE, Mintz EL, Latvis CR, Shepherd BR, Presnell SC, McConnell MJ, Highley C, Peirce SM, Christ GJ. (2020) Bioprinting on sheet-based scaffolds applied to the creation of implantable tissue-engineered constructs with potentially diverse clinical applications: Tissue-Engineered Muscle Repair (TEMR) as a representative testbed. Connect Tissue Res. Jan 3:1-13. PMID: 31899969.
Peirce SM and Marsden A. (2020) Multiscale computational modeling of biomedical systems: current approaches and payoffs. Current Opinion in Biomedical Engineering. Vol. 11, A1-A3.
Warner HV, Sivakumar N, Peirce SM, Lazzara MJ. (2020) Multiscale computational models of cancer. Current Opinion in Biomedical Engineering. Vol. 11, p. 137-144.
Talman L, Agmon E, Peirce SM, Covert MW (2020) Multiscale models of infection. Current Opinion in Biomedical Engineering. Vol. 11, p. 102-108.
2019
Rikard SM, Athey TL, Nelson AR, Christiansen SLM, Lee JJ, Holmes JW, Peirce SM, Saucerman JJ. (2019) Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling. Front Physiol. 2019 Dec 17;10:1481. PMID:31920691
Renardy M, Wessler T, Blemker S, Linderman J, Peirce S, Kirschner D. (2019) Data-Driven Model Validation Across Dimensions. Jun;81(6):1853-1866. PMID: 30830675
Corliss BA, Ray HC, Mathews C, Fitzgerald K, Doty RW, Smolko CM, Shariff H, Peirce SM, Yates PA. (2019) Myh11 Lineage Corneal Endothelial Cells and ASCs Populate Corneal Endothelium. Invest Ophthalmol Vis Sci. Dec 2;60(15):5095-5103. PMID: 31826231
Hess DL, Kelly-Goss MR, Cherepanova OA, Nguyen AT, Baylis RA, Tkachenko S, Annex BH, Peirce SM, Owens GK. (2019) Perivascular cell-specific knockout of the stem cell pluripotency gene Oct4 inhibits angiogenesis. Nat Commun. Feb 27;10(1):967. doi: 10.1038/s41467-019-08811-z. PMID: 30814500
Corliss BA, Delalio LJ, Stevenson Keller TC 4th, Keller AS, Keller DA, Corliss BH, Beers JM, Peirce SM, Isakson BE. (2019) Vascular Expression of Hemoglobin Alpha in Antarctic Icefish Supports Iron Limitation as Novel Evolutionary Driver. Front Physiol. Nov 12;10:1389. PMID: 31780954
Corliss BA, Mathews C, Doty R, Rhode G, Peirce SM. (2019) Methods to Label, Image, and Analyze the Complex Structural Architectures of Microvascular Networks. Microcirculation. Jul;26(5):e12520. PMID: 30548558
Urner S, Planas-Paz L, Hilger LS, Henning C, Branopolski A, Kelly-Goss M, Stanczuk L, Pitter B, Montanez E, Peirce SM, Mäkinen T, Lammert E. (2019) Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth.EMBO J. Jan 15;38(2). pii: e99322. doi: 10.15252/embj.201899322. PMID: 30518533
Lee JJ, Talman L, Peirce SM, Holmes JW. (2019) Spatial scaling in multiscale models: methods for coupling agent-based and finite-element models of wound healing. Biomech Model Mechanobiol. Oct;18(5):1297-1309. PMID: 30968216
Corliss BA, Ray HC, Patrie JT, Mansour J, Kesting S, Park JH, Rohde G, Yates PA, Janes KA, Peirce SM (2018)
CIRCOAST: a statistical hypothesis test for cellular colocalization with network structures. Bioinformatics. Feb 1;35(3):506-514. PMID: 30032263
2018
Sun N, Ning B, Hansson KM, Bruce AC, Seaman SA, Zhang C, Rikard M, DeRosa CA, Fraser CL, Wågberg M, Fritsche-Danielson R, Wikström J, Chien KR, Lundahl A, Hölttä M, Carlsson LG, Peirce SM, Hu S. (2018) Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing. Sci Rep. Nov 30;8(1):17509. PMID: 30504800
Suarez-Martinez AD, Peirce SM, Isakson BE, Nice M, Wang J, Lounsbury KM, Scallan JP, Murfee WL.
(2018) Induction of microvascular network growth in the mouse mesentery. Microcirculation. 2018
Nov;25(8):e12502. PMID: 30178505
Virgilio KM, Martin KS, Peirce SM, Blemker SS. (2018) Agent-based model illustrates the role of the microenvironment in regeneration in healthy and mdx skeletal muscle. J Appl Physiol. Nov 1;125(5):1424-1439. PMID: 30070607
Tavakol DN, Broshkevitch CJ, Guilford WH, Peirce SM. (2018) Design and implementation of a student-taught course on research in regenerative medicine. Adv Physiol Educ. Jun 1;42(2):360-367. PMID: 29761714
Haskins RM, Nguyen AT, Alencar GF, Billaud M, Kelly-Goss MR, Good ME, Bottermann K, Klibanov AL, French BA, Harris TE, Peirce SM, Isakson BE, Owens GK. (2018) Klf4 has an unexpected protective role in perivascular cells within the microvasculature. Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H402-H414. PMID: 29631369
Danan D, Lehman CE, Mendez RE, Langford B, Koors PD, Dougherty MI, Peirce SM, Gioeli DG, Jameson MJ. (2018) Effect of Adipose-Derived Stem Cells on Head and Neck Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2018 May;158(5):882-888. PMID: 29313435
Urner S, Kelly-Goss M, Peirce SM, Lammert E. (2018) Mechanotransduction in Blood and Lymphatic Vascular Development and Disease. Adv Pharmacol. 2018;81:155-208. doi: 10.1016/bs.apha.2017.08.009. PMID: 29310798
Smith HK, Omura S, Vital SA, Becker F, Senchenkova EY, Kaur G, Tsunoda I, Peirce SM, Gavins FNE
(2018) Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke. FASEB J. 2018 May;32(5):2381-2394. PMID: 29269399
Adamson SE, Montgomery G, Seaman SA, Peirce-Cottler SM, Leitinger N. (2018) Myeloid P2Y2 receptor promotes acute inflammation but is dispensable for chronic high-fat diet-induced metabolic dysfunction. Purinergic Signalling. Mar;14(1):19-26. PMID: 29086245
2017
Kelly-Goss MR, Ning B, Bruce AC, Tavakol DN, Yi D, Hu S, Yates PA, Peirce SM. (2017) Dynamic, heterogeneous endothelial Tie2 expression and capillary blood flow during microvascular remodeling. Scientific Reports. Aug 22;7(1):9049. PMID: 28831080
Walpole J, Gabhann FM, Peirce SM, Chappell JC. (2017) Agent-based computational model of retinal angiogenesis simulates microvascular network morphology as a function of pericyte coverage. Microcirculation. Nov;24(8). PMID: 28791758
Hannan RT, Peirce SM, Barker TH. (2017) Fibroblasts: diverse cells critical to biomaterials integration. ACS Biomaterial. Sci. Eng. Apr 9;4(4):1223-1232. PMID: 31440581
Janes KA, Chandran PL, Ford RM, Lazzara MJ, Papin JA, Peirce SM, Saucerman JJ, Lauffenburger DA. (2017) An engineering design approach to systems biology. Integr. Biol. 9(7):574-583. PMID: 28590470
Murfee WL, Peirce SM. (2017) Microfluidics technologies and approaches for studying the microcirculation. Microcirculation. 24(5). PMID: 28470950
Varhue WB, Langman L, Kelly-Goss M, Lataillade M, Brayman KL, Peirce-Cottler SM, Swami NS. (2017) Deformability-based microfluidic separation of pancreatic islets from exocrine acinar tissue for transplant applications. Lab on a Chip. Oct 25;17(21):3682-3691. PMID: 28975176
Urner S, Kelly-Goss M, Peirce SM, Lammert E. (2017) Mechanotransduction in blood and lymphatic vascular development and disease. Advances in Pharmacology. 81:155-208. PMID: 29310798
DeGeorge BR Jr, Ning B, Salopek LS, Pineros-Fernandez A, Rodeheaver GT, Peirce-Cottler S, Hu S, Cottler PS, Campbell CA. (2017) Advanced imaging techniques for investigation of acellular dermal matrix biointegration. Plastic and Reconstructive Surgery, 139(2):395-405. PMID: 28121875
Henry CC, Martin KS, Ward BB, Handsfield GG, Peirce SM, Blemker SS. (2017) Spatial and age-related changes in the microstructure of dystrophic and healthy diaphragms. PLoS One. 6;12(9):e0183853. PMID: 28877195
Olingy CE, San Emeterio CL, Ogle ME, Krieger JR, Bruce AC, Pfau DD, Jordan BT, Peirce SM, Botchwey EA. (2017) Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury. Scientific Reports. 27;7(1):447. PMID: 28348370
Call JA, Donet J, Martin KS, Sharma AK, Chen X, Zhang J, Cai J, Galarreta CA, Okutsu M, Du Z, Lira VA, Zhang M, Mehrad B, Annex BH, Klibanov AL, Bowler RP, Laubach VE, Peirce SM, Yan Z. (2017) Muscle-derived extracellular superoxide dismutase inhibits endothelial activation and protects against multiple organ dysfunction syndrome in mice. Free Radic Biol Med. 2017 Oct 2;113:212-223. doi: 10.1016/j.freeradbiomed.2017.09.029. PMID: 28982599
2016
DeRosa CA, Seaman SA, Mathew AS, Gorick CM, Fan Z, Demas JN, Peirce SM, Fraser CL. (2016) Oxygen sensing difluoroboron β-diketonate polylactide materials with tunable dynamic ranges for wound imaging. ACS Sensors. 1(11):1366-1373.
Seaman SA, Cao Y, Campbell CA, Peirce SM. (2016) Arteriogenesis in murine adipose tissue is contingent on CD68+ /CD206+ macrophages. Microcirculation. 24(4).
Seaman SA, Cao Y, Campbell CA, Peirce SM. (2016) Macrophage recruitment and polarization during collateral vessel remodeling in murine adipose tissue. Microcirculation. 23(1):75-87.
Seaman SA, Tannan SC, Cao Y, Peirce SM, Gampper TG. (2016) A closer look at cryolipolysis-induced paradoxical adipose hyperplasia and cellular effects—evidence of more than adipocyte cell death. Aesthetic Surgery Journal. 36(1):NP6-NP13.
Corliss BA, Azimi MS, Munson J, Peirce SM, Murfee WL. (2016) Macrophages: an inflammatory link between angiogenesis and lymphangiogenesis. Microcirculation. 23(2):95-121.
Chappell JC, Cluceru JG, Nesmith JE, Mouillesseaux KP, Bradley V, Hartland C, Hashambhoy-Ramsay YL, Walpole JB, Peirce SM, Mac Gabhann F, Bautch VL. (2016) Flt-1 (VEGFR-1) coordinates discrete stages of blood vessel formation. Cardiovascular Research. 111(1):84-93.
Bruce A, Cao Y, Henry C, Peirce SM, Laughon K. (2016) Pre-clinical assessment of safety and efficacy of fluorescent dye for detecting dermal abrasions in a murine model. Journal of Forensic Sciences. 61(6):1493-1497.
Martin K., Virgilio K., Peirce-Cottler S., Blemker S. (2016) Computational modeling of muscle regeneration and adaptation to advance muscle tissue regeneration strategies. Cells, Tissues, Organs. 202(3-4):250-266.
Martin KS, Kegelman CD, Virgilio KM, Passipieri JA, Christ GJ, Blemker SS, Peirce SM. (2016) In silico and in vivo experiments reveal M-CSF injections accelerate regeneration following muscle laceration. Ann Biomed Eng. 45(3):747-760.
Kingsmore KM, Logsdon DK, Floyd DH, Peirce SM, Purow BW, Munson JM. (2016) Interstitial flow differentially increases patient-derived glioblastoma stem cell invasion via CXCR4, CXCL12, and CD44-mediated mechanisms. Inter Biol. 8(12):1246-1260.
2015
Walpole J, Chappell JC, Clucerub JG, Mac Gabhann F, Bautch VL, Peirce SM. (2015) Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks. Integrative Biology. 7: 987-997.
Martin KS, Blemker SS, Peirce SM. (2015) Agent-based computational model of skeletal muscle investigates muscle-specific responses to disuse-induced muscle atrophy. J Appl Physiol. 118(10):1299-309.
Virgilio KM, Martin KS, Peirce SM, Blemker SS. (2015) Multi-scale models of skeletal muscle reveal the complex effects of muscular dystrophy on tissue mechanics and damage susceptibility. Interface Focus. 5(2):20140080.
Murfee WL, Sweat RS, Tsubota K , Mac Gabhann F, Khismatullin S, Peirce SM. (2015) Applications of computational models to better understand microvascular remodeling. Interface Focus. 5(2):20140077.
Heuslein JL, Li X, Murrell KP, Annex BH, Peirce SM, Price RJ. (2015) Computational network model prediction of hemodynamic alterations due to arteriolar rarefaction and estimation of skeletal muscle perfusion in peripheral arterial disease. Microcirculation. Apr 10. doi: 10.1111/micc.12203. [Epub ahead of print]
Cronk S, Mendel TA, Hoehn KL, Ray CH, Bruce A, Guendel AM, Herman IM, Peirce SM, Yates PA. (2015) Adipose-derived stem cells from diabetic sources show impaired vascular stabilization in the treatment of diabetic retinopathy. Stem Cells Translational Medicine. 4(5):459-67.
Seaman SA, Tannan ST, Cao Y, Peirce SM, Lin KY. (2015) Differential effects of processing time and duration of collagenase digestion on human and murine fat grafts. Journal of Plastic Surgery Research. Aug;136(2):189e-99e.
Adamson SE, Meher AK, Chiu Y, Sandilos JK, Oberholtzer NP, Walker NN, Hargett SR, Seaman SA, SM Peirce-Cottler, Isakson BE, Macnamara CA, Keller SR, Harris TE, Bayliss DA, Leitinger N. (2015) Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes. Molecular Metabolism. 4(9):610-8.
2014
Bruce AC, Kelly-Goss MR, Heuslein JL, Meisner JK, Price RJ, Peirce SM. (2014) Monocytes are recruited from venules during arteriogenesis in the murine spinotrapezius ligation model. Arterioscler Thromb Vasc Biol. 34(9):2012-22.
Kelly-Goss MR, Sweat RS, Stapor PC, Peirce SM, Murfee WL. (2014) Targeting pericytes for angiogenic therapies. Microcirculation. May;21(4):345-57.
Agrawal A, Shang H, Parker AM, Ying N, Peirce SM, Katz AJ. (2014) Human adipose-derived cells demonstrate short-lived persistence after implantation in both an immunocompetent and an immunocompromised murine model. Stem Cell Research & Therapy. 5(6):142.
Kesser BW, Hallman M, Murphy L, Tillar M, Keeley M, Peirce S. (2014) Interval vs massed training: how best do we teach surgery? Otolaryngol Head Neck Surg. 150(1):61-7.
Okutsu M, Call JA, Lira VA, Zhang M, Donet JA, French BA, Martin KS, Peirce-Cottler SM, Rembold CM, Annex BH, Yan Z. (2014) Extracellular superoxide dismutase ameliorates skeletal muscle abnormalities, Cachexia and Exercise Intolerance in Mice with Congestive Heart Failure. Circ Heart Fail. 7(3):519-30.
Ogle ME, Sefcik LS, Awojoodu AO, Chiappa NF, Lynch K, Peirce-Cottler S, Botchwey EA. (2014) Engineering in vivo gradients of sphingosine-1-phosphate receptor ligands for localized microvascular remodeling and inflammatory cell positioning. Acta Biomater. 10(11):4704-14.
2013
Awojoodu AO, Ogle ME, Sefcik LS, Bowers DT, Martin K, Brayman KL, Lynch KR, Peirce-Cottler SM, Botchwey E. (2013) Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13785-90.
Mendel TA, Clabough EBD, Kao DS, Demidova-Rice TN,Durham JT, Zotter BC, Seaman SA, Cronk SM, Rakoczy EP, Katz AJ, Herman IM, Peirce SM, Yates PA. (2013) Pericytes derived from adipose-derived stem cells protect against retinal vasculopathy. PLoS One. 8(5):e65691. PMID: 23741506
Walpole J, Papin JA, Peirce SM. (2013) Multiscale computational models of complex biological systems. Annu Rev Biomed Eng. 15:137-54.
Guendel AM, Martin KS, Cutts J, Foley PL, Bailey AM, Mac Gabhann F, Cardinal TR, Peirce S. (2013) Murine spinotrapezius model to assess the impact of arteriolar ligation on microvascular function and remodeling. J Vis Exp. Mar 3;(73):e50218. doi: 10.3791/50218.
2012
Peirce SM, Mac Gabhann F, Bautch VL. (2012) Integration of experimental and computational approaches to sprouting angiogenesis. Curr Opin Hematol. 2012 May;19(3):184-91. doi: 10.1097/MOH.0b013e3283523ea6.
Taylor AC, Mendel TA, Mason KE, Degen KE, Yates PA, Peirce SM. (2012) Attenuation of ephrinB2 reverse signaling decreases vascularized area and preretinal vascular tuft formation in the murine model of oxygen-induced retinopathy.13;53(9):5462-70. doi: 10.1167/iovs.11-8599.
Yang M, Stapor PC, Peirce SM, Betancourt AM, Murfee WL. (2012) Rat mesentery exteriorization: a model for investigating the cellular dynamics involved in angiogenesis. J Vis Exp. 2012 May 20;(63):e3954. doi: 10.3791/3954.
Morris E, Kesser BW, Peirce-Cottler S, Keeley M. (2012) Development and validation of a novel ear simulator to teach pneumatic otoscopy.Simul Healthc. Feb;7(1):22-6. doi: 10.1097/SIH.0b013e31822eac39.
Hayenga HN, Thorne BC, Yen P, Papin JA, Peirce SM, Humphrey JD. (2012) Multiscale computational modeling in vascular biology: from molecular mechanisms to tissue-Level structure and function. Springer-Verlag Berlin Heidelberg. Series 8415. Stud Mechanobiol Tissue Eng Biomater. doi: 10.1007/8415_2012_147
2011
Bruce AC, Peirce SM. (2011) Exogenous thrombin delivery promotes collateral capillary arterialization and tissue reperfusion in the murine spinotrapezius muscle Ischemia model. Microcirculation. Feb;19(2):143-54. doi: 10.1111/j.1549-8719.2011.00138.x.
Amos PJ, Mulvey CL, Seaman S, Walpole J, Degen KE, Shang H, Katz AJ, Peirce-Cottler SM. (2011) Hypoxic culture and in vivo inflammatory environments affect the assumption of pericyte characteristics by human adipose and bone marrow progenitor cells. Am J Physiol Cell Physiol. Dec;301(6):C1378-88. doi: 10.1152/ajpcell.00460.2010.
Hayenga HN, Thorne BC, Peirce SM, Humphrey JD. (2011) Ensuring congruency in multiscale modeling: towards linking agent based and continuum biomechanical models of arterial adaptation. Ann Biomed Eng. 2011 Nov;39(11):2669-82. Epub 2011 Aug 2.
Thorne BC, Hayenga HN, Humphrey JD, Peirce SM. (2011) Toward a multi-scale computational model of arterial adaptation in hypertension: verification of a multi-cell agent based model. Front Physiol. 2011;2:20. Epub 2011 May 9.
Hashambhoy YL, Chappell JC, Peirce-Cottler SM, Bautch VL, Mac Gabhann F. (2011) Computational modeling of interacting VEGF and soluble VEGF receptor concentration gradients. Front Physiol. 2011;2:62. doi: 10.3389/fphys.2011.00062.
Seaman ME, Peirce SM, Kelly K. (2011) Rapid analysis of vessel elements (RAVE): a tool for studying physiologic, pathologic and tumor angiogenesis. PLoS One. 2011;6(6):e20807. Epub 2011 Jun 9.
Sefcik LS, Aronin CE, Awojoodu AO, Shin SJ, Mac Gabhann F, MacDonald TL, Wamhoff BR, Lynch KR, Peirce SM, Botchwey EA. (2011) Selective activation of sphingosine 1-phosphate receptors 1 and 3 promotes local microvascular network growth. Tissue Eng. Part A. Mar;17(5-6):617-29. Epub 2010 Nov 9.
Billaud M, Ross JA, Greyson MA, Bruce AC, Seaman SA, Heberlein KR, Han J, Best AK, Peirce SM, Isakson BE. (2011) A new method for in vivo visualization of vessel remodeling using a near-infrared dye. Microcirculation. Apr;18(3):163-71. doi: 10.1111/j.1549-8719.2011.00085.x.
Benedict KF, Mac Gabhann F, Amanfu RK, Chavali AK, Gianchandani EP, Glaw LS, Oberhardt MA, Thorne BC, Yang JH, Papin JA, Peirce SM, Saucerman JJ, & Skalak TC. (2011) Systems analysis of small signaling modules relevant to eight human diseases. Ann Biomed Eng. 39(2):621-35.
2010
Taylor AC, Seltz LM, Yates PA, & Peirce SM. (2010) Chronic whole-body hypoxia induces murine retinal angiogenesis and microvascular remodeling. Microvascular Research. 79(2):93-101.
Amos PJ, Kapur SK, Stapor PC, Hulan S, Bekiranov S, Rodeheaver GT, Peirce SM, & Katz AJ. (2010) Human adipose-derived Stem cell aggregates as a therapy for healing diabetic wounds. Tissue Engineering Part A. 16(5):1595-606.
Petrie Aronin C, Sefcik LS, Tholpady A, Sadik KW, Tholpady SS, Macdonald TL, Wamhoff BR, Peirce SM, Lynch KR, Ogle R, & Botchwey E. (2010) FTY720 promotes local microvascular network formation and regeneration of cranial bone defects. Tissue Eng Part A. Jun;16(6):1801-9.
Mac Gabhann F & Peirce SM. (2010) Anatomical predictions of capillary arterialization in mouse spinotrapezius muscle based on mouse strain. Microcirculation. 17:333-47.
Glaw J, Skalak TC, & Peirce SM. (2010) Inhibition of canonical Wnt signaling in microvascular growth and remodeling of an adult rat mesenteric model. Microcirculation. 17:348-57.
2009
Bailey AM, Lawrence MB, Shang H, Katz AJ, & Peirce SM. (2009) Agent-based model of therapeutic adipose-derived stromal cell trafficking during ischemia predicts P-selectin mediated rolling ability. PLoS Computational Biology. Feb 5 (2):e1000294.
Volsky PG, Hughley B, Peirce SM, & Kesser BW. (2009) Construct validity of a simulator for myringotomy and ventilation tube insertion. Otolaryngology-Head and Neck Surgery, Otolaryngol Head Neck Surg. 41(5):603-608.e1.
2008
Chavali AK, Gianchandani EP, Tung KS, Lawrence MB, Peirce SM, & Papin JA. (2008) Modeling of complex immunological systems for characterizing global emergent properties. Trends in Immunology. 29(12):589-99.
Peirce SM. (2008) Computational and mathematical modeling of angiogenesis. Microcirculation. 15(8):739-51, 2008. PMID: 18720228.
Birchenough S.A., Rodeheaver G.T., Morgan R.F., Peirce S.M., Katz A.J. (2008). Topical poloxamer-188 improves blood flow following thermal injury in rat mesenteric microvasculature. Ann Plast Surg 5,584-588.
Bailey A.M., O'Neill T.J.t., Morris C.E., Peirce S.M. (2008). Arteriolar remodeling following ischemic injury extends from capillary to large arteriole in the microcirculation. Microcirculation 5,389-404.
Amos P.J., Shang H., Bailey A.M., Taylor A., Katz A.J., Peirce S.M. (2008). IFATS Series: The role of human adipose-derived stromal cells in inflammatory microvascular remodeling and evidence of a perivascular phenotype. Stem Cells.
Amos PJ*, Bailey AM*, Shang H, Katz AJ, Lawrence MB, and Peirce SM. Functional binding of human adipose-derived stromal cells: Effecs of extraction method and hypoxia pretreatment. Annals of Plastic Surgery. Volume 60(4), April 2008, pp 437-444. >> Authors contributed equally to this work.
Thorne BC, Bailey AM, DeSimone DW, & Peirce SM. (2008). Agent-based modeling of multi-cell morphogenic processes during development. Embryo Today, Jan; 81(4):344-353.
2007
Robertson SH, Smith CK, Langhans AL, McLinden SE, Oberhardt MA, Jakab KR, Dzamba B, DeSimone DW, Papin JA, & Peirce SM. (2007). Multiscale computational analysis of Xenopus laevis morphogenesis reveals key insights of systems-level behavior. BMC Syst Biol, Oct; 1:46.
Thorne, B. C., Bailey, A. M. and Peirce, S. M. (2007). Combining experiments with multi-cell agent-based modeling to study biological tissue patterning. Brief Bioinform, Jul; 8(4): 245-57.
Taylor, A. C., Murfee, W. L. and Peirce, S. M. (2007). EphB4 expression along adult rat microvascular networks: EphB4 is more than a venous specific marker. Microcirculation 14, 253-67.
Bailey, A. M.*, Thorne, B. C.* and Peirce, S. M. (2007). Multi-cell agent-based simulation of the microvasculature to study the dynamics of circulating inflammatory cell trafficking. Ann Biomed Eng 35, 916-36. *Authors contributed equally to this work.
2006
Peirce-Cottler, S.M., T.S. Skalak, and J.A. Papin. 2006. Multi-scale systems integration from cells to tissues: coupling intracellular network analysis with tissue-patterning simulations. IBM Journal of Research and Development.
Murfee WL, Rehorn MR, & Peirce SM, Skalak TC, 2006. Perivascular cells along venules upregulate NG2 expression during microvascular remodeling. Microcirculation. 13: 261-273.
2005
Murfee WL, Skalak TC, & SM Peirce, 2005. Differential arterial/venous expression of NG2 proteoglycan in perivascular cells along microvessels: identifying a venule-specific phenotype. Microcirculation 12: 151-160.
2004
Peirce SM*, Van Gieson EJ*, & Skalak TC, 2004. Multicellular simulation predicts microvascular patterning and in silico tissue assembly. FASEB Journal.10.1096/fj.03-0933fje. *Authors contributed equally to this work.
Longo DM*, Peirce SM*, Skalak TC, Marsden M, Davidson LA, Dzamba BJ, & DeSimone DW, 2004. Computational automata simulation of blastocoel roof thinning In the Xenopus laevis embryo. Developmental Biology. 271: 210-222. *Authors contribtued equally to this work.
2003
Peirce SM & Skalak TC, 2003. Microvascular remodeling: A complex continuum spanning angiogenesis to arteriogenesis. Microcirculation. 10: 99-111.
Peirce SM, Price RJ, & Skalak TC, 2003. Spatial and temporal guidance of angiogenesis and arterialization. American Journal of Physiology-Heart & Circulatory Physiology. 286: H918-H925.
2002
Hirschi KK, Skalak TC, Peirce SM, & Little CD, 2002. Vascular assembly in natural and engineered tissues. Annals New York Academy of Sciences. 961: 223-242.
2000
Peirce SM, Skalak TC, & Rodeheaver G, 2000. Ischemia-reperfusion injury in chronic pressure ulcer formation: a skin model in the rat. Wound Repair and Regeneration, 1(8): 90-97.
Peirce SM, Skalak TC, MacDonald T, Reiger J, & Linden J, 2000. Selective A2A adenosine receptor activation reduces skin pressure ulcer formation and inflammation. American Journal of Physiology- Heart & Circulatory Physiology. 281(1): H67-74.